Association mapping and disease: evolutionary perspectives.
نویسندگان
چکیده
In this chapter, we give a short introduction to the genetics of complex disease with special emphasis on evolutionary models for disease genes and the effect of different models on the genetic architecture, and finally give a survey of the state-of-the-art of genome-wide association studies.
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عنوان ژورنال:
- Methods in molecular biology
دوره 856 شماره
صفحات -
تاریخ انتشار 2012